This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie Grant Agreement No 764860.
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George Sideris-Lampretsas (ESR1) and Marzia Malcangio have published a literature review in Science Direct on Brain behavior and Immunity entitled “Microglial heterogeneity in chronic pain“

Marzia Malcangio – Inflammatory pain and microglial activity in Alzheimer’s disease.
Camilla Svensson – Role of Bone Remodeling in Non-Inflammatory Pain-Related Behaviors By Collagen Antibody-Induced Arthritis Model
Hans-Georg Schaible – Contribution of Inflammation, Bone Destruction and Neuronal Challenge to Pain in the Model of Glucose 6 Phospate Isomerase-Induced Arthritis
Claudia Sommer – Translational Aspects of Neuroimaging in Pain
ESR5 Zerina Kurtovic presented her paper
‘Immune cells in the dorsal root ganglia could be important contributors to sex differences in pain biology of the rheumatoid arthritis model CAIA’ for the European Pain School 14-19 June 2021
ESR4 Joana Menezes presented her paper ‘Autoantibodies – a novel contributor to pain in Fibromyalgia?
14th to 19th June 2021
ESR2 Xhoana Lama took part in the Parkinson’s UK Virtual lab tour and talks with Professor Susan Duty’s Lab Team: “Making sense of the science” on the 13th May 2021. Xhoana presented ‘Understanding neuroinflammation in pain in Parkinson’s‘
The Project Repository Journal (PRj) is now online
The latest TOBeATPAIN article written by Marzia Malcangio can be found on page 72 of this ninth edition.
Zerina Kurtovic (ESR5) participates in a 3-MT competition
One of the aims of the 3-MT competition is to challenge PhD students to present their research to a non-scientific audience in 3 minutes. The idea is to explain one’s project in an understandable manner without dumbing it down. BH 3-MT is the first time a competition of this type was organized in Bosnia and Herzegovina and it was truly a pleasure to try to disseminate my research to people in my home country. It was a particularly joyful experience because I contributed to putting science on the agenda of public discussion. I feel really honored to have won 1st Prize in the Public Voting part of the competition with more than 4K likes on YouTube and 15K views. You can watch my video on the following link:
‘Exploring novel macrophage-associated mechanisms in autoantibody-induced pain’
Silvia Fanton (ESR3) is the first-author of a TOBeATPAIN paper in PAIN and now also available on PubMed:
Presentations by TOBeATPAIN Research Fellows
Jeiny Luna-Choconta ESR6
Microglia plasticity in a mouse model of Fabry disease exploring the role of macrophages and microglial cells during the progression of FD in the dorsal root ganglion, the spinal cord and brain in a murine transgenic model of FD.
Patricia García Fernández ESR9
Expression Analysis of a Pro-Inflammatory Pathway in Neuropathic Pain
This studies the hypothesis that the immune system may be involved in the development of pain in patients with neuropathies
Fátima Gimeno-Ferrer ESR8
Calcitonin Gene-Related Peptide (CGRP) Influences Cortical Neuronal Excitability Dose-Dependently in Rodents
Investigating the role of neuroinflammation in nociception in the full and partial 6-hydroxydopamine lesioned rat models of Parkinson’s disease
ESR12 Rita Silva
Impaired Pain-like Behaviour in Animal Model of Alzheimer’s Disease Following Peripheral Nerve Injury
The TOBeATPAIN Winter School took place on the 27th, 28th and 29th January 2021. This was a virtual event hosted by Prof. Michaela Kress at the Medizinische Universitat Innsbruck.
Topics covered included Neurodegenerative diseases, Rheumatic diseases and Peripheral neuropathies.
Guest speakers included
Prof. John Hardy, Chair of Molecular Biology of Neurological Disease, University College London
Prof. Marco Prinz, Institute of Neuroopathologie, University Medical Centre, Frieburg
Prof. Richard M. Ransohoff MD Third Rock Ventures, Boston
